BREVETTI ANGELA has closely collaborated
with many in the pharmaceutical industry to address their needs for
primary packaging. The fruits of its intense effort at the cutting-edge
of technology are realised in the latest generation of blow-fill-seal
equipment series called SYFPAC® and LIQUIDPAC. Simultaneously, other packaging equipment, viz. FLUIPAC, CYNOPAC, MECAS, BAGPAC and SACKPAC, have also been developed by Brevetti Angela.
Aseptic packaging has to be done with special care and with the aim of eliminating microbiological and particulate contamination from the solution. Personnel is the greatest source of contamination in a parenteral production environment as they generate human dust. Particular attention must be paid, especially in the vicinity of an open container during filling, to maintain low contamination levels.
The Blow-Fill-Seal Technique has been developed so that formation of
the container, filling and sealing takes place in a single machine under
a controlled environment that enables the packaging of a pharmaceutical
liquid in an aseptic manner, with the following advantages:
• less overall floor space requirement.
• lower personnel requirements.
• lower clean room requirements.
• better protection of product from contamination.
• lower logistic problems in the procurement and storage of the empty container.